My last work during the postdoc time @ NKI published in Nature Communication, entitled:

Genomic data integration by WON-PARAFAC identifies interpretable factors for predicting drug-sensitivity in vivo

The method uses a cube-representation of multiple genomics data (gene by sample by data types) and apply a variant of parallel-factor analysis (PARAFAC), named WON-PARAFAC.

WONPARAFAC summarizes multiple genomics data of cell lines using interpretable factors. These factors are invariant over model systems and capable of reconstructing PDX genomics data; moreover, they allow for response prediction and translate predictive drug-response information from cell lines to PDXs.

Overview of the approach

You can find the source code in MATLAB at the Wessel’s group website (NKI) and also at the Github repository.